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Clonal heterogeneity of endocrine therapy resistance in breast cancer

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Zenodo2023-03-29 更新2026-04-07 收录
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https://zenodo.org/record/7780929
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资源简介:
We barcoded endocrine therapy sensitive cell lines (MCF7 and T47D) and rendered them resistant to commonly applied first line endocrine therapeutics (Tamoxifen and estrogen deprivation). Next, we isolated single cell clones of endocrine therapy resistant populations and subjected clonal cell lines to RNA-Seq and Phosphoproteomics profiling.
提供机构:
German Cancer Research Center-Division of Molecular Genome Analysis; German Cancer Research Center-Cellular Tools Core Facility; German Cancer Research Center-Division of Somatic Evolution and Early Detection; Weizmann Institute of Science-Department of Immunology and Regenerative Biology; German Cancer Research Center-Mass Spectrometry Core Facility
创建时间:
2023-03-29
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