epithelia and fibroblasts gene profile in 4NQO induced tongue carcinogenesis

Nine groups of rat tongue epithelia and submucosal fibroblasts RNA samples respectively, including three from normal control, three from dysplasia, and three from carcinoma (3 rats per group) were collected for gene microarray hybridization.本研究分别采集了大鼠舌上皮细胞及黏膜下成纤维细胞的RNA样本各9组，每类样本均分为正常对照组、上皮异型增生组、癌组各3组，每组均来自3只大鼠，所有样本均用于基因芯片杂交实验。