APP/PS1 Mouse Brain Effects of ADAM17

NIAID Data Ecosystem2026-03-14 收录

阿尔茨海默病模型

基因治疗

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Affects of ADAM17 AAV9 mediated injection on cognitive and vascular function in the APP/PS1 mouse model of Alzheimer's disease.

创建时间：

2023-03-02

Additional file 9: of Viral-mediated gene delivery of TMBIM6 protects the neonatal brain via disruption of NPR-CYP complex coupled with upregulation of Nrf-2 post-HI

基因治疗

神经保护

Statistical analysis of IL-1β and MPO positive cells at 72 h post-HI. Representative table showing detailed statistical analysis from immunohistochemistry experiments measuring the expression of IL-1β

DataCite Commons2020-08-26 更新150

Programmable RNA base editing with a single engineered protein

碱基编辑

基因治疗

Programmable base editing of RNA enables rewriting the genetic codes on specific sites. Current tools for specific RNA editing dependent on the assembly or recruitment of the guide RNA into an RNA/pro

NIAID Data Ecosystem40

Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome.

腺病毒载体

基因治疗

An efficient method of constructing recombinant adenoviruses (Ads) has been established. The expression unit to be introduced into recombinant Ad was first inserted into the unique Swa I site of the f

PubMed Central1996-02-06 更新30

Aging African Green Monkeys manifest transcriptional, pathological, and cognitive hallmarks of human Alzheimer’s disease

阿尔茨海默病模型

灵长类衰老转录组

While many preclinical models of Alzheimer’s disease (AD) have been reported, none fully recapitulate the disease. In an effort to identify an appropriate preclinical disease model, we characterized a

NIAID Data Ecosystem50

Additional file 7 of Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer’s mouse models

阿尔茨海默病模型

微生物组

Additional file 7: Table S2. PERMANOVA results for main figures.

Figshare2024-08-16 更新40