In this study, we report pre-existing human CD8+ T cell immunity to Streptococcus pyogenes Cas9 in the majority of healthy individuals screened. In a proof-of-principle study, we demonstrate that Cas

NIAID Data Ecosystem70

Defining Essential Enhancer for Pluripotent stem cells using Features Oriented CRISPR-Cas9 Screen (RNA-Seq 2)

多能干细胞增强子鉴定

CRISPR-Cas9功能研究

Cis Regulatory Elements (CREs) regulate the expression of the genes in their genomic neighborhoods and influence cellular processes such as cell-fate maintenance and differentiation. To date, there re

NIAID Data Ecosystem70

Massively Parallel Genetic Disruption of Enhancers Active During Human Corticogenesis

发育遗传学

CRISPR-Cas9功能研究

Changes in gene regulation have been linked to the expansion of the human cerebral cortex and to neurodevelopmental disorders. However, the biological effects of genetic variation within developmental

NIAID Data Ecosystem70

PpCas9 from Pasteurella pneumotropica - a compact Type II-C Cas9 ortholog active in human cells. Part 2

CRISPR-Cas9功能研究

基因工程工具开发

Characterization Type II-C CRISPR Cas systems from Defluviimonas sp. 20V17 and Pasteurella pneumotropica. Illumina sequencing reads from PpCas9 specificity tests.

NIAID Data Ecosystem70

Data for: A genome-wide CRISPR/Cas9 screen reveals that riboflavin regulates hydrogen peroxide entry into HAP1 cells

资源简介：

相关数据集