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The levels of differentially expressed miRNAs in the rat sufferred from myocardial ischemia or administrated with choline after ischemia.

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Male Wistar rats were divided into control, ischemia and choline chloride (choline, agonist of M3-mAChR) groups. Myocardial ischemia model was induced for 24 h. Choline (10 mg/kg, i.v.) was administrated 10 min before occlusion. After 24 h ischemia, ventricular tissues were dissected for miRNA microarray analysis. MiRNAs levels were calculated based on the normalization to control group (set as 1).

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2012-03-02
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