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Transcription profiling by array of spleen samples from male and female BWF1 lupus-prone mice to investigate sex hormone regulated genes

ChEBI2007-12-04 更新2026-07-21 收录

狼疮动物模型

性激素基因调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-2336 数据链接链接失效反馈

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资源简介：

Transcription profiling by array of spleen samples from male and female BWF1 lupus-prone mice to investigate sex hormone regulated genes

应用场景：

创建时间：

2007-12-04

狼疮动物模型

性别差异表达

We report loss of epigentic silencing marks on the inactive X on female mice with lupus like disease, and find novel sex differences in gene expression between female and male mice with late stage dis

NIAID Data Ecosystem30

Fecal microbiota from MRL/Lpr mice exacerbates pristane induced lupus

自身免疫病微生物组

狼疮动物模型

The 16s rRNA sequence and metagenome sequencing of the gut microbiome of the the pristane-induced lupus mice with fecal microbiota transplantation from MRL/Lpr mice or MRL/Mpj mice

Mendeley Data00

we engineered a long-acting bioavailable enzyme biologic with dual DNASE1 and DNASE1L3 activity and tested the biologic in murine genetic and non-genetic models of lupus and acute autoinflammatory disease. A dual acting DNASE1 enzyme biologic prevents autoimmunity and death in murine models of lupus and diffuse alveolar hemorrhage

狼疮动物模型

NETs清除疗法

A defining feature of lupus is the loss of tolerance to self-DNA, and extracellular chromatin extruded by neutrophils, called NETs, have been proposed as a putative antigenic driver of lupus autoimmun

NIAID Data Ecosystem00

stool Raw sequence reads

消化道微生物组

狼疮动物模型

gut microbiota in lupus mice

NIAID Data Ecosystem10

Comparison of metagenome sequencing of 6- and 16-week-old MRL/lpr mice

狼疮动物模型

消化道微生物组

MRL/lpr mice are known to have progressively worsening lupus symptoms starting at 6 weeks of age. We compared the gut microbiota of 6-week-old mice before and 16-week-old mice after lupus symptoms app

NIAID Data Ecosystem00

Transcription profiling by array of spleen samples from male and female BWF1 lupus-prone mice to investigate sex hormone regulated genes

资源简介：

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