DNA methylation profiling of 82 triple negative breast cancers with BRCA1 promoter methylation or BRCA1 mutation using the Illumina EPIC 850K platform.

Genome-wide DNA methylation profiles for 82 triple negative breast cancer (TNBC) samples from the Swedsh Cancerome Analysis Network - Breast (SCAN-B) cohort. Genomic DNA from 82 triple negative breast cancer (TNBC) samples was treated with bisulfite and hybridized to Illumina EPIC 850K arrays using standard protocols. Raw iDat files were processed using the minfi-package in R as well as custom R-scripts to produce normalized beta values. Both raw intensity values from minfi and the final normalized data are included for each sample.