Comparison of once daily versus twice daily administration of PTK787/ZK 222584 in mCRC
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https://www.omicsdi.org/dataset/ecrin-mdr-crc/2520622
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Primary objectives: The primary objective is to compare the pharmacodynamic activity of PTK787/ ZK 222584 by dynamic contrast-enhanced (DCE)-magnetic resonance imaging (MRI) at trough levels in once daily (o.d.) versus twice daily (b.i.d.) treatment arms.
Primary endpoints: The primary efficacy variable is the number of patients with at least 40% reduction in Ktrans from baseline to Day 28.
创建时间：
2007-02-15
