RNAseq analysis highlights significant transcriptional changes within the livers of patients with alcoholic hepatitis.. RNAseq analysis highlights significant transcriptional changes within the livers of patients with alcoholic hepatitis.

Alcoholic hepatitis (AH) is frequently a severe clinical condition associated with high short-term mortality. This study was meant to serve as a resource for AH investigators in an effort to increase understanding of this disease and treatment research (NIH Project # 5R24AA025017). Overall design: Explanted livers from patients with acute alcoholic hepatits were sampled by RNAseq, and relative gene abundance was compared to samples derived from donor livers.