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Hair follicle development: cytodifferentiation - stage 3 of 3

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wikipathways.github.io2025-03-25 收录
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The hair follicle (HF) is the biological unit responsible for producing a single hair shaft. The follicles are arranged with concentric epithelial progenitor layers surrounding the dermal core, which is the dermal papilla (DP). Classically, the development of the follicle itself can be divided into three stages: [https://www.wikipathways.org/index.php/Pathway:WP2804 Induction], [https://www.wikipathways.org/index.php/Pathway:WP2839 Organogenesis] and Cytodifferentiation. Hair follicle cytodifferentiation is the third main step in hair follicle development and leads to the formation of the bulbous peg. Source: [https://www.ncbi.nlm.nih.gov/books/NBK45997/ Notch signaling and the developing hair follicle, by Geneviève Aubin-Houzelstein]

毛囊(HF)是负责产生单个毛发干状的生物学单元。毛囊由同心圆排列的上皮祖细胞层环绕着真皮核心,即真皮乳头(DP)。传统上,毛囊的发育过程可分为三个阶段:[https://www.wikipathways.org/index.php/Pathway:WP2804 诱导],[https://www.wikipathways.org/index.php/Pathway:WP2839 发育形成]以及[https://www.wikipathways.org/index.php/Pathway:WP2839 细胞分化]。毛囊细胞分化是毛囊发育过程中的第三主要步骤,导致毛球状物的形成。资料来源:[https://www.ncbi.nlm.nih.gov/books/NBK45997/ 《-notch 信号通路与毛囊发育》一文,作者:Geneviève Aubin-Houzelstein]
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