Our study presents a spatial-stochastic model for the gene regulatory network (GRN) and the signaling pathway governing cell-fate differentiation during early mouse embryogenesis, specifically at the
c0 is the background concentration, a is the typical linear size of a cell, β and μ are the production and degradation rates of the reporters, is the slope of the gradient [18, 19, 43].
Single-cell approaches are revealing a high degree of heterogeneity, or noise, in gene expression in isogenic bacteria. How gene circuits modulate this noise in gene expression to generate robust outp