Integrated transcriptome, proteome, metabolome and microbiome analyses identify multi-omics signature of glycolipid metabolism disorder: a cross-sectional study

We collected blood/stool samples from 30 patients with type 2 diabetes and dyslipidemia (GL), 30 patients with hyperlipidemia (HL), and 30 healthy controls, conducted transcriptome/proteome/metabolome/microbiome analysis, and correlated it with clinical phenotypes. We further integrated multi-omics features and tested the discriminant efficacy of multi-omics datasets using ROC curves.