Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with SAM and allosteric inhibitor compound 2
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with SAM and allosteric inhibitor compound 2 Descriptor: 5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one, CHLORIDE ION, S-ADENOSYLMETHIONINE, ... Authors: Padyana, A, Jin, L. Deposit date: 2020-10-05 Release date: 2021-04-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.14 Å) Cite: Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous MTAP Deletion. J.Med.Chem., 64, 2021
创建时间：
2020-10-05
