Additional file 7 of Modulation of innate immunity related genes resulting in prophylactic antimicrobial and antiviral properties

Additional file 7. Related to Figure S2B. Biological processes related to the proteins of the interaction network generated via the Search Tool for the Retrieval of Interacting Genes/ Proteins (STRING) database ( https://string-db.org ) by using proteins encoded by those DEGs taking part to ‘pathway in cancer’ in KEGG pathway enrichment analyses performed on RNAseq data obtained from Caco-2 cells treated with Solution-3 (0.01x) or vehicle (0.8% NaCl) for 24 hours (see Additional file 5-6). The proteins belonging to biological processes involved in immune system and inflammation are indicated in bold: positive regulation of immune system process (GO:0002684, fdr = 0.0011), inflammatory response (GO:0006954, fdr = 0.0049), leukocyte differentiation (GO:0002521, fdr = 0.0051), regulation of T cell differentiation in thymus (GO:0033081, fdr = 0.0057), response to cytokine (GO:0034097, false discovery rate [fdr] = 0.0107), mononuclear cell differentiation (GO:1903131, fdr = 0.0110) regulation of phagocytosis (GO:0050764, fdr = 0.0112), cytokine-mediated signaling pathway (GO:0019221, fdr = 0.0197), cellular response to cytokine stimulus (GO:0071345, fdr = 0.0208), myeloid leukocyte differentiation (GO:0002573, fdr = 0.0228), leukocyte migration (GO:0050900, fdr = 0.0236), positive regulation of T cell differentiation in thymus (GO:0033089, fdr = 0.0268), regulation of leukocyte activation (GO:0002694, fdr = 0.0342), alpha-beta T cell differentiation (GO:0046632, fdr = 0.0394), T cell differentiation (GO:0030217, fdr = 0.0433) and positive regulation of phagocytosis (GO:0050766, fdr = 0.0448). The term ID, the term description, the observed gene count, the background gene count, the strength, the false discovery rate (frd) and the matching proteins in the network are shown.