Study of mucosa-associated microbiota in post-operative recurrence of Crohn's disease

16S rRNA (V3-V4) and ITS2 sequencing was performed on ileal biopsies from a prospective multicentre study conducted by the REMIND group and aimed at identifying predictors of early postoperative endoscopic recurrence. Patients were recruited across 14 centers in France between February 2017 and June 2020. Inclusion criteria were age>18 years, ileal or ileo-colonic CD, and an indication of CD-related intestinal surgery (ileocolonic resection) in the absence of intestinal dysplasia or cancer.