The significance of quercetin-loaded advanced nanoformulations for the management of diabetic wounds - supplementary table

Quercetin is a well-known plant flavanol that exhibits multiple biological activities, including antioxidant,
anti-inflammatory and anticancer activities. The role of quercetin in wound healing has been widely
explored by a range of researchers in different models. However, the physicochemical properties, such
as solubility and permeability, of this compound are low, which ultimately limits its bioavailability on the
target site. To overcome these limitations for successful therapy, scientists have developed a range of
nanoformulations that provide effective therapeutic potential. In this review, the broad mechanism of
quercetin for acute and chronic wounds is covered. A compilation of recent advances on the horizon of
wound healing via quercetin is incorporated with several advanced nanoformulations.