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Epistasis between drug resistance-conferring mutations in Mycobacterium tuberculosis

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP177380
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To analysze epistatic interactions between high-level RpoB and GyrA drug resistance mutations in Mycobacterium tuberculosis, starting from nine genetically distinct drug susceptible isolates of MTBC L1, L2 and L4, we picked single- and double-drug resistant mutants carrying RpoB and or GyrA drug resistance mutations alone and in combination.
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2026-01-20
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