Gene variants in B6 mice caused by integration of the IAPLTR1a_Mm sequence.
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BLAT search with 338 bp of the IAPLTR1a_Mm sequence identified 202 integrations into the B6 genome (90 retrotransposons flanked with LTR sequences and 22 isolated LTR sequences). Thirty-three of the integrations were located in introns of genes. In 8 transcripts modifications caused by the LTR motive were identified; 6 led to a truncated mRNA, and 2 generated an alternative transcription start. Variants in the Adamts13 mRNA caused by the IAPLTR1a_Mm sequence were previously described [27].
创建时间:
2015-12-02



