Alternative splicing isoforms in patient-derived hepatocellular carcinoma cells
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https://www.omicsdi.org/dataset/ega/EGAS00001002697
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资源简介：
The aim of this study was to obtain a landscape of alternative splicing (AS) in human hepatocellular carcinoma (HCC). We applied hybrid sequencing by integrating Pacbio long-read and Illumina short-read RNA sequencing data from 8 patient-derived HCC cell lines, and used an immortalized hepatocyte cell line as reference. This study revealed features of annotated and novel splice variants in HCC cells, including transcript length, AS type and protein changes. We also identified novel isoforms and tumor specific isoforms, which may represent potential biomarkers and targets for therapeutic development.EGA study EGAS00001002697
创建时间：
2019-01-30
