Potent and selective isophthalamide S2 hydroxyethylamine inhibitor of BACE1
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Potent and selective isophthalamide S2 hydroxyethylamine inhibitor of BACE1 Descriptor: Beta-secretase 1, N~3~-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-N~1~,N~1~-DIPROPYLBENZENE-1,3,5-TRICARBOXAMIDE, PHOSPHATE ION Authors: Benson, T.E, Prince, D.B, Tomasselli, A.G, Emmons, T.L, Paddock, D.J. Deposit date: 2007-03-21 Release date: 2007-06-19 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Potent and selective isophthalamide S(2) hydroxyethylamine inhibitors of BACE1. Bioorg.Med.Chem.Lett., 17, 2007
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2007-03-21
