Gene expression patterns that form the basis for the observed variation in islet density among porcine pancreata were examined. RNA-Seq analysis was performed to investigate differential gene expressi

NIAID Data Ecosystem70

Next Generation Sequencing Facilitating Quantitative Analysis of Wild Type (Kcnj11fl/fl, WT) and β-cell Specific Kcnj11 -/- (βKcnj11 -/-, bKO) Mouse Islets' Transcriptomes. Next Generation Sequencing Facilitating Quantitative Analysis of Wild Type (Kcnj11fl/fl, WT) and β-cell Specific Kcnj11 -/- (βKcnj11 -/-, bKO) Mouse Islets' Transcriptomes

胰腺转录组学

基因敲除小鼠转录组

β-cell Specific Kcnj11 -/- mice and their islets exhibited a hirtherto unkown switch in the major signaling pathway of G-protein coulpled receptors from Gs to Gq, and overall enhanced Gq signaling. Th

NIAID Data Ecosystem50

Circadian gene expression profile of pancreatic islets from C57BL6 mice fed on rodent chow diet collected at 4hr intervals around the clock

昼夜节律基因表达

胰腺转录组学

Comparison of pancreatic islet transcriptome at 4hr intervals around the clock helps to identify genes that are cycling under the control of the circadian clock. We used Agilent microarrays to analyze

NIAID Data Ecosystem100

Transcriptomic profiling of alpha, beta, and delta cell populations provides new insights into the role of ghrelin in the pancreas

胰腺转录组学

ghrelin信号通路

Intra-islet crosstalk between islet cells is critical in orchestrating the bodyâs response to changes in blood glucose levels, but is incompletely understood. In this study, we used transgenic mouse

NIAID Data Ecosystem60

e7e65d5e-3838-4bba-be42-90e8012bc3a7 - samples

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