Crystal structure of BTK mutant (F435T,K596R) complexed with Imidazo[1,5-a]quinoxaline
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Crystal structure of BTK mutant (F435T,K596R) complexed with Imidazo[1,5-a]quinoxaline Descriptor: (2Z)-4-(dimethylamino)-N-{7-fluoro-4-[(2-methylphenyl)amino]imidazo[1,5-a]quinoxalin-8-yl}-N-methylbut-2-enamide, GLYCEROL, Tyrosine-protein kinase ITK/TSK Authors: Han, S, Caspers, N. Deposit date: 2011-08-03 Release date: 2011-10-12 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis. Bioorg.Med.Chem.Lett., 21, 2011
创建时间：
2011-08-03
