Tankyrase-2 in complex with RK-582
收藏Protein Data Bank Japan2024-03-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6kro
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Tankyrase-2 in complex with RK-582 Descriptor: 6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-4-fluoranyl-1-methyl-1'-(8-methyl-4-oxidanylidene-3,5,6,7-tetrahydropyrido[2,3-d]pyrimidin-2-yl)spiro[indole-3,4'-piperidine]-2-one, GLYCEROL, PHOSPHATE ION, ... Authors: Niwa, H, Shirai, F, Sato, S, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T. Deposit date: 2019-08-22 Release date: 2020-04-01 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer. J.Med.Chem., 63, 2020
创建时间：
2019-08-22
