Lactate Dehydrogenase in complex with inhibitor compound 13

Lactate Dehydrogenase in complex with inhibitor compound 13 Descriptor: (5R)-2-[(2-chlorophenyl)sulfanyl]-5-[2,6-dichloro-3-(tetrahydro-2H-pyran-4-ylamino)phenyl]-3-hydroxycyclohex-2-en-1-one, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Eigenbrot, C, Ultsch, M. Deposit date: 2014-08-22 Release date: 2014-12-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.19 Å) Cite: Optimization of 5-(2,6-dichlorophenyl)-3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase. Bioorg.Med.Chem.Lett., 25, 2014