RNA-seq (CAFs stimulated with control or HNRNPK knockdown supernatants)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE197540
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资源简介：
Purpose: The goals of this study are to invsetigate the primary signaling pathway enriched in CAFs after stimulation of LUAD supernatants. Methods: Briefly, the supernatants (HNRNPK knockdown and control) of H1299 cells were incubated with CAFs for 24h. Then the CAFs were used to extract total RNAs for quality control and RNA-seq loading samples. RNA-seq was performed as DGE on an Illumia HiSeq platform and 50 bp paired-end reads were generated (BGI Co. Ltd.). Results: Gene Ontology (GO) analysis revealed that cell proliferation and migration were identified as the biological functions of HNRNPK Conclusions: In CAFs, we confirmed that the PI3K-AKT signaling pathway was significantly enriched after stimulation of H1299 supernatants. mRNA profiles of CAFs stimulated with control or HNRNPK knockdown supernatants
创建时间：
2022-12-09
