The molecular classification of glioblastoma (GBM) based on gene expression might better explain outcome and response to treatment than clinical factors. Whole transcriptome sequencing using next-gene
A table listing all detected PI3K alterations in the cohort. The majority of alterations were reported in COSMIC ( https://cancer.sanger.ac.uk/cosmic/browse/genome ) and/or occured at hospot locations
Glioblastoma (GBM) is an incurable brain tumor carrying a dismal prognosis, which displays considerable heterogeneity. We have recently identified recurrent H3F3A mutations affecting two critical posi