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Additional file 5 of CRISPR-Cas13d screens identify KILR, a breast cancer risk-associated lncRNA that regulates DNA replication and repair

NIAID Data Ecosystem2026-05-02 收录

CRISPRi筛选

乳腺癌分子机制

数据链接：

https://figshare.com/articles/dataset/Additional_file_5_of_CRISPR-Cas13d_screens_identify_KILR_a_breast_cancer_risk-associated_lncRNA_that_regulates_DNA_replication_and_repair/25824714 数据链接链接失效反馈

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资源简介：

Supplementary Material 5

应用场景：

创建时间：

2024-05-15

乳腺癌分子机制

性激素受体结合位点

We performed chromatin immunoprecipitation (ChIP) with overnight with antibodies against the C-terminus (HC-20, from Santa Cruz Biotechnology, Europe) or the N-terminus (anti-Estrogen Receptor 18-32,

NIAID Data Ecosystem50

Additional file 12 of Identification of functional regulatory elements in the human genome using pooled CRISPR screens

CRISPRi筛选

功能调控元件识别

Additional file 12: Table S7. CRISPR screen raw read counts (Peak Library/dCas9-KRAB).

NIAID Data Ecosystem20

Targeting SUMO2 reverses aberrant epigenetic rewiring driven by SS18::SSX fusion oncoproteins and impairs sarcomagenesis [CRISPR Screening]

滑膜肉瘤治疗

CRISPRi筛选

Synovial sarcoma (SySa) is an aggressive soft tissue sarcoma with an urgent need to develop targeted therapies. Here, we exploited specific vulnerabilities created by transcriptional rewiring by the f

NIAID Data Ecosystem10

JMJD6 licenses estrogen receptor alpha-dependent enhancer RNA and coding gene activation by modulating CARM1/MED12 co-activator complex in breast cancer

癌症转录调控

乳腺癌分子机制

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem20

Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.. Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.

乳腺癌分子机制

受体信号通路

Inhibitory crosstalk between estrogen receptor alpha (ER alpha ) and aryl hydrocarbon receptor (AHR) regulates 17-estradiol (E2)-dependent breast cancer cell signaling. ER alpha and AHR are transcript

NIAID Data Ecosystem10

Additional file 5 of CRISPR-Cas13d screens identify KILR, a breast cancer risk-associated lncRNA that regulates DNA replication and repair

资源简介：

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