[3+2] Cycloaddition Reactions in the Solid-Phase Synthesis of 1,2,3-Triazoles
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An efficient and regioselective procedure for the synthesis of 1,2,3-triazoles via a [3+2] cycloaddition of polymer-bound vinyl sulfone and sodium azide is described. Microwave irradiation provided significant rate enhancement in all steps of the three-step protocol. A representative set of 23 compounds was prepared.
创建时间:
2016-03-01



