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Amorfrutins are selective PPARM-NM-3 agonists with potent antidiabetic properties

ChEBI2012-05-01 更新2026-07-21 收录

糖尿病药物发现

PPARα激动剂

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-28384 数据链接链接失效反馈

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Amorfrutins are selective PPARM-NM-3 agonists with potent antidiabetic properties

应用场景：

创建时间：

2012-05-01

代谢研究

PPARα激动剂

Comparison of metabolic parameters measured in rats with aging or PPARγ agonist treatment.

NIAID Data Ecosystem80

Imidazopyridine and Pyrazolopiperidine Derivatives as Novel Inhibitors of Serine Palmitoyl Transferase

糖尿病药物发现

血脂异常治疗

To develop novel treatments for type 2 diabetes and dyslipidemia, we pursued inhibitors of serine palmitoyl transferase (SPT). To this end compounds 1 and 2 were developed as potent SPT inhibitors in

NIAID Data Ecosystem40

Natural extracts with described antidiabetic activity that contain one molecule that is predicted to be a PPARγ partial agonist by our virtual screening protocol.

天然药物筛选

PPARα激动剂

The Table shows the natural extracts (i.e., third column) and the VS hits that have been purified from them (identified by their common name, when available, and CAS number). The bibliographic referen

NIAID Data Ecosystem20

Molecular characterization of novel peroxisome proliferator-activated receptor alpha agonists. Mus musculus

PPARα激动剂

脂质代谢调控

The nuclear receptor PPARalpha is recognized as the primary target of the fibrate class of hypolipidemic drugs and mediates lipid lowering in part by activating a transcriptional cascade that induces

NIAID Data Ecosystem50

North America PPARδ Agonist Market

药物靶点市场分析

PPARα激动剂

The report on North America PPARδ Agonist covers a summarized study of several factors supporting market growth, such as market size, market type, major regions, and end-user applications. The report

IMR REPORTS30

Amorfrutins are selective PPARM-NM-3 agonists with potent antidiabetic properties

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