DNA variants that influence gene expression shape phenotypic variation. Trans-acting variants affect target genes that can be located anywhere in the genome, and may specifically affect their mRNA or
MaveDB is a public repository for datasets from Multiplexed Assays of Variant Effect (MAVEs), such as those generated by deep mutational scanning (DMS) or massively parallel reporter assay (MPRA) expe
Noncoding genetic variation is a major driver of phenotypic diversity but determining the underlying mechanisms and the cell types in which it acts remain challenging problems. Here, we investigate th
The purpose of the experiment is to quantify the dynamic of transcriptional response to galactose exposure by flow cytometric analysis of single yeast cells expressing a GFP reporter system. We aim i)
