Structure of Acipimox-GPR109A-G protein complex

Structure of Acipimox-GPR109A-G protein complex Descriptor: 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. Deposit date: 2023-05-16 Release date: 2024-03-06 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution. Nat Commun, 15, 2024