ACAT2 x-ray
收藏DataCite Commons2025-07-24 更新2025-09-08 收录
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https://figshare.com/articles/dataset/ACAT2_x-ray/29640800/1
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资源简介：
Phenotypic screening identified a site-specific (Y237) and regioselective SuPUR ligand of ACAT2 to reveal an unexpected metabolic dependency in cancer cells. A crystal structure of SuPUR ligand-bound ACAT2 revealed the purine group binds deep in the CoA pocket forming key interactions with catalytic residues via a water bridge to guide future structure-based ligand design.
提供机构：
figshare
创建时间：
2025-07-24
