[2.2]Paracyclophane-Derived Monodentate Phosphoramidite Ligands for Copper-Catalyzed Asymmetric Conjugate Addition of Diethylzinc to Substituted Chalcones
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https://figshare.com/articles/dataset/_2_2_Paracyclophane_Derived_Monodentate_Phosphoramidite_Ligands_for_Copper_Catalyzed_Asymmetric_Conjugate_Addition_of_Diethylzinc_to_Substituted_Chalcones/2175466
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资源简介:
Copper-catalyzed
asymmetric conjugate addition of diethylzinc to
chalcones could be realized by using [2.2]paracyclophane-derived monodentate
phosphoramidite ligands. The excellent yield and enantioselectivity
(up to 98% yield and 95% enantiomeric excess) could be realized with
low catalyst loading of 1.0 mol % and low ligand loading of 1.2%.
创建时间:
2016-02-13



