Supplementary data to "High-Resolution Raman Imaging of >300 Patient-Derived Cells from Nine Different Leukemia Subtypes: A Global Clustering Approach"

Compressed ".feather" files including the entire dataset of 319 Raman maps of the same number of cells from 19 patients affected by nine distinct leukemia subtypes.Raw data have been pre-processed as follows using custom software (LabVIEW, National Instruments Corp., TX): a) cosmic rays removal by singular value decomposition (SVD); b) camera offset subtraction; c) CCD response correction (intensity and etaloning) using a tungsten halogen light with known emission (Avalight-HAL, Avantes BV, NL)); d) wavenumber calibration using the zero-wavenumber laser line, toluene and argon-mercury emission (CAL-2000, Ocean Optics, Germany); e) denoising by SVD.More details in the open access published article and supplementary material (10.1021/acs.analchem.4c00787).