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Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (CD2) complexed with NF2657

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (CD2) complexed with NF2657 Descriptor: Hdac6 protein, N-hydroxy-4-[(1-methyl-1,2-dihydro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)methyl]benzamide, POTASSIUM ION, ... Authors: Osko, J.D, Christianson, D.W. Deposit date: 2019-12-08 Release date: 2020-12-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.08741757573 Å) Cite: Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation. Acs Med.Chem.Lett., 11, 2020
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2019-12-08
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