The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with Estradiol and a glucocorticoid receptor-interacting protein 1 NR box II peptide
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https://pdbj.org/mine/summary/4pxm
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The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with Estradiol and a glucocorticoid receptor-interacting protein 1 NR box II peptide Descriptor: ESTRADIOL, Estrogen receptor, Nuclear receptor coactivator 2 Authors: Fanning, S.W, Panchamukhi, S, Greene, G.L. Deposit date: 2014-03-24 Release date: 2015-04-08 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation. Elife, 5, 2016
创建时间：
2014-03-24
