Comparison of the percent change over time versus the percent difference in benign and malignant tissue.

THb = total hemoglobin; s’> = reduced scattering coefficient; A = adipose; P = positive malignant; FA = fibroadipose; FG = fibroglandular.Comparison of the percent change in each optical parameter at 10, 20, and 30 minutes post-excision to the percent differences between 1) adipose and positive sites, 2) fibroadipose and positive sites, and 3) fibroglandular and positive sites from our initial site-level study [43], [44]. A negative value in the percent difference indicates that positive sites were greater; a positive value means the benign tissue was greater.