five

DMD monkey model gene therapy. Macaca mulatta

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下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1015347
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Firstly, a DMD monkey model with exon 50 mutation was constructed using CRISPR/Cas9 to analyze whether CRISPR/Cas9 caused off-target. Then, the gene repair of the targeted exon 51 was carried out, and the target efficiency and off-target were analyzed, so as to prove the safety of the therapeutic gene.
创建时间:
2023-09-11
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