Crystal structure of the cAMP-dependent protein kinase A cocrystallized with isoquinoline-5-carboxylic acid and PKI (5-24)
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Crystal structure of the cAMP-dependent protein kinase A cocrystallized with isoquinoline-5-carboxylic acid and PKI (5-24) Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, isoquinoline-5-carboxylic acid Authors: Oebbeke, M, Wienen-Schmidt, B, Heine, A, Klebe, G. Deposit date: 2020-11-10 Release date: 2021-11-24 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Fragment based drug design - Small chemical changes of fragments effecting big changes in binding To Be Published
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2020-11-10
