Rhodium(III)-Catalyzed Intermolecular Direct Amidation of Aldehyde C–H Bonds with N‑Chloroamines at Room Temperature

A Rh(III)-catalyzed direct aldehyde C–H amidation from aldehydes and N-chloroamines, prepared in situ from amines, has been developed via C–H bond activation under very mild reaction conditions. A variety of primary and secondary amines were used to afford the corresponding amides in moderate to excellent yields.