five

Aspirin Pharmacogenomics

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https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000548.v1.p1
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The study protocol for both cohorts has been previously described (Journal of Thrombosis and Thrombolysis 2012:1-12). HV1 cohort: Briefly 50 healthy volunteers were exposed to two weeks of 325mg/day aspirin after which whole blood RNA was collected in PAXgene tubes and profiled by microarray before and after aspirin exposure. The pre-aspirin samples were profiled on the U133A 2.0 array and the post-aspirin samples were profiled on the U1333plus 2.0 array. HV2 cohort: Briefly 53 healthy volunteers were exposed to four weeks of 325mg/day aspirin after which whole blood RNA was collected in PAXgene tubes and profiled by U133plus 2.0 array before and after aspirin exposure. ]]> The study protocol for both cohorts has been previously described (Journal of Thrombosis and Thrombolysis 2012:1-12).]]> The study protocol for both cohorts has been previously described (Journal of Thrombosis and Thrombolysis 2012:1-12).]]>
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2012-10-01
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