Figure 1

Monash University Figshare2023-06-28 更新2026-07-07 收录

UBA5缺乏症神经病理

线粒体功能障碍

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https://bridges.monash.edu/articles/dataset/Figure_1/20744875 数据链接链接失效反馈

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Raw and supporting data for Figure 1 in Genetic model of UBA5 deficiency highlights involvement of both peripheral and central nervous systems and identifies widespread mitochondrial pathology

创建时间：

2022-09-28

Erratum: The Antioxidant N-Acetylcysteine Prevents the Mitochondrial Fragmentation Induced by Soluble Amyloid-F Peptide Oligomers

阿尔茨海默病分子机制

线粒体功能障碍

Background: Soluble amyloid-F peptide oligomers (AFOs), which are centrally involved in the pathogenesis of Alzheimer’s disease, trigger Ca2+ influx through N-methyl-D-aspartate receptors and stimulat

Figshare2017-07-25 更新50

TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

神经退行性机制

线粒体功能障碍

Mutations in or dys-regulation of the TDP-43 gene have been associated with TDP-43 proteinopathy, a spectrum of neurodegenerative diseases including Frontotemporal Lobar Degeneration (FTLD) and Amyotr

Figshare2019-05-17 更新20

ERR agonism reverses mitochondrial dysfunction and inflammation in the aging kidney

肾脏衰老机制

线粒体功能障碍

A gradual decline in renal function occurs even in healthy aging individuals. In addition to aging per se, concurrent metabolic syndrome and hypertension, which are common in the aging population, can

NIAID Data Ecosystem00

The genetic background shapes disease susceptibility and reveals a specific role for mitochondrial dysfunction in the progression from NAFLD to NASH

非酒精性脂肪肝病

线粒体功能障碍

Non-alcoholic steatohepatitis (NASH) is a global health concern without treatment. The challenge in finding effective therapies is due to the lack of good mouse models and the complexity of the diseas

Mendeley Data30

PSMF1 variants cause a phenotypic spectrum from early-onset Parkinson’s disease to perinatal lethality and disrupt mitochondrial pathways

帕金森病遗传学

线粒体功能障碍

Dissecting biopathways unveiled by Mendelian gene discovery has provided critical insights into the pathogenesis of Parkinson’s disease (PD) and neurodegeneration, hence catalyzing the identification

NIAID Data Ecosystem10

Figure 1

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