LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (drug combination treatments). Dataset 1 of 2: Cell count and normalized growth rate inhibition values.

As described in HMS LINCS Datasets #20245-20252, measures of the sensitivities of six cell lines to a library of small molecule inhibitors were generated by treating cells with single drugs at six doses starting at 10 µM in 3x dilution steps and measuring cell number after three days of drug exposure. Based on those results, a subset of the drugs was chosen for analysis of combinatorial drug sensitivities in a single cell line (Datasets #20259 and #20260). As part of this LINCS Pilot Phase Joint Project, L1000 gene expression data generated by the Broad LINCS Center for the same perturbagen combinations are available at http://projects.lincscloud.org/#LJP.