Liver ATAC-seq data

The liver is central to regulating nitrogen utilization efficiency (NUE), defined as the ratio of milk nitrogen yield (g/d) to nitrogen intake (g/d) in dairy cows. Identifying the regulatory elements in the liver that affect nitrogen utilization is essential for understanding the factors influencing NUE.This study employed RNA sequencing (RNA-seq) and assay for transposase-accessible chromatin sequencing (ATAC-seq) to profile the liver transcriptome and chromatin accessibility in primiparous lactating cows with divergent NUE.