The X chromosome provides an ideal model system to study the contribution of RNA-protein interactions in epigenetic regulation. In male flies, roX lncRNAs harbor several redundant domains to interact

NIAID Data Ecosystem30

Photoactive G‑Quadruplex Ligand Identifies Multiple G‑Quadruplex-Related Proteins with Extensive Sequence Tolerance in the Cellular Environment

G-四链体分析

核酸二级结构功能

G-Quadruplex (G4) is a noncanonical nucleic acid secondary structure with multiple biofunctions. Identifying G4-related proteins (G4RPs) is important for understanding the roles of G4 in biology. Curr

Figshare2021-01-20 更新20

DHX36 is the missing link to understand RNA G-quadruplex structures, mRNA stability, and translation [RNA-seq]

核酸二级结构功能

RNA稳定性调控

DHX36 is a ATP-dependent, 3´-5´ RNA helicase of the DEAH family. Previous publications reported this helicase to associate with AU-rich elements and to specifically unwind G-quadruplex structures. Her

NIAID Data Ecosystem50

Secondary structure of the ribosome binding site determines translational efficiency: a quantitative analysis.

翻译效率调控

核酸二级结构功能

We have quantitatively analyzed the relationship between translational efficiency and the mRNA secondary structure in the initiation region. The stability of a defined hairpin structure containing a r

PubMed Central20

Genomic identifiers and oligonucleotide sequences used in CD spectroscopy.

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