Single-cell RNA-sequencing of Mettl14 conditional knock-out retinas and matched controls
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https://www.ncbi.nlm.nih.gov/sra/SRP379908
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资源简介：
Post-transcriptional m6A methylation on mRNA plays a key role in neural development. Here, we specifically depleted Mettl14 (a key component of m6A complex) in retina progenitor cells by crossing Mettl14 fl/fl mice with the Chx10-Egfp/Cre mouse line and investigated cell type and transcriptome changes in the developing retinas using scRNA-seq. Overall design: Retinas of Mettl14 fl/fl;Chx10-Egfp/Cre (Mettl14-cKO) mice and age matched controls were collect at P7 and applied to scRNA-seq.
创建时间：
2023-09-01
