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Enantioselective Addition of Alkynes to α,α-Dichlorinated Aldehydes

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NIAID Data Ecosystem2026-03-10 收录
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https://figshare.com/articles/dataset/Enantioselective_Addition_of_Alkynes_to_-Dichlorinated_Aldehydes/4591729
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资源简介:
Enantioselective addition of terminal alkynes to α,α-dichlorinated aldehydes employing Zn­(OTf)2/NME is disclosed. The propargylic alcohols obtained are accessed in good yields and high enantioselectivity from easily accessible α,α-dichloroaldehydes. The method opens new strategic opportunities for the synthesis of chlorinated natural products, such as the chlorosulfolipids.
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2017-01-27
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