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Female sex and oestrogen receptor β attenuate cardiac remodelling and apoptosis in pressure overload

ChEBI2010-01-19 更新2026-07-21 收录

心脏重塑机制

性别差异心血管病理

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-18224 数据链接链接失效反馈

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资源简介：

Female sex and oestrogen receptor β attenuate cardiac remodelling and apoptosis in pressure overload

应用场景：

创建时间：

2010-01-19

RNA结合蛋白靶标

心脏重塑机制

Mutations or decreased expression of RNA-binding proteins (mRBPs) can lead to cardiomyopathies in humans. Here we defined RBPs in healthy and diseased primary cardiomyocytes at a system-wide level by

NIAID Data Ecosystem90

Serial and regional assessment of the right ventricular molecular and functional response to pressure-loading

右心室压力负荷

心脏重塑机制

Background: Right ventricular(RV) function determines outcomes in RV pressure-loading. A better understanding of the time-course and regional distribution of RV remodeling may help optimize targets an

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PR_M_Based线粒体孕酮受体心脏β_氧化与重塑研究数据

能量代谢

心脏重塑机制

本数据集为线粒体孕酮受体（PR-M）相关研究的补充资料，涵盖PR-M在大鼠心肌细胞中调控氧化呼吸、β-氧化的实验结果，以及转基因小鼠模型中心脏重塑、能量代谢相关基因表达和主动脉缩窄模型下心功能保护的研究数据，用于支撑PR-M介导孕酮调控心脏能量生产与重塑的科学结论。论文“A mitochondrial progesterone receptor increases cardiac beta-ox

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Ratio of heart weight to body weight and plasma angiotensin II in sham, tachycardia (Tachy) and volume-overload (VOL) HF animals.

心力衰竭动物模型

心脏重塑机制

P value is the comparison of tachycardia and volume-overload groups with sham. RV: right ventricle. LV: left ventricle. BW: body weight Ang II: angiotensin II.

NIAID Data Ecosystem70

DataSheet1.pdf

心脏重塑机制

心力衰竭代偿机制

The cardiac system compensates for variations in physiological and pathophysiological conditions through a dynamic remodeling at the organ, tissue, and intracellular levels in order to maintain functi

NIAID Data Ecosystem50

Female sex and oestrogen receptor β attenuate cardiac remodelling and apoptosis in pressure overload

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