The ΔyscN gene deletion in <i>Y. pestis</i> CO92 creates a fully attenuated ΔyscN CO92 strain in a mouse model of bubonic plague.
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Groups of 10 Swiss-Webster female mice were inoculated s.c. with the deletion mutant and observed for 21 days as described under Materials and Methods. Data are statistically valid (p<0.05). For control experiments, the animals were challenged with 180 CFU of wt Y. pestis CO92 strain as described under Materials and Methods.
创建时间：
2011-05-18
