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Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor

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Protein Data Bank Japan2023-10-25 更新2026-03-21 收录
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Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor Descriptor: Genome polyprotein, N-[(13-CYCLOHEXYL-6,7-DIHYDROINDOLO[1,2-D][1,4]BENZOXAZEPIN-10-YL)CARBONYL]-2-METHYL-L-ALANINE Authors: Adachi, T, Tsuruha, J, Doi, S, Murase, K, Ikegashira, K, Watanabe, S, Uehara, K, Orita, T, Nomura, A, Kamada, M. Deposit date: 2006-08-30 Release date: 2006-12-26 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of Conformationally Constrained Tetracyclic Compounds as Potent Hepatitis C Virus NS5B RNA Polymerase Inhibitors J.Med.Chem., 49, 2006
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2006-08-30
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